VINZENZ GRUPPE
     
 

Signal-averaged electrocardiography in patients with AL (primary) amyloidosis.

Dubrey, S W, Bilazarian, S, LaValley, M, Reisinger, J, Skinner, M and Falk, R H (1997) Signal-averaged electrocardiography in patients with AL (primary) amyloidosis. American heart journal, 134 (6). pp. 994-1001. ISSN 0002-8703

Full text not available from this repository.

Abstract

One hundred thirty-three patients with biopsy-proven AL amyloidosis were studied with echocardiography, Holter recording, 12-lead electrocardiography, and signal-averaged electrocardiograms. Features from these tests were analyzed in relation to their effect on mortality. Late potentials were more frequent in patients with echocardiographic evidence of cardiac amyloidosis (31%) compared with patients with normal echocardiograms (9%, p < 0.003). One hundred six of the 133 patients died during follow-up, of which 34 were nonsudden cardiac deaths and 33 were sudden deaths. Abnormal echocardiograms and signal-averaged electrocardiograms were each predictive of all-cause cardiac death (p < 0.0001 ) and sudden cardiac death (p < 0.0001). Abnormal signal-averaged electrocardiograms were also independently predictive of sudden death in the subgroup of patients with an abnormal echocardiogram (p < 0.05). Thus late potentials are predictive of sudden death in patients with AL amyloidosis and provide independent prognostic information in patients with echocardiographic evidence of amyloid involvement.
Item Type: Article
Subjects: WG Kardiovaskuläres System
Depositing User: Dr. Christian Vogel
Date Deposited: 15 Nov 2012 09:10
Last Modified: 15 Nov 2012 09:10
URI: https://eprints.vinzenzgruppe.at/id/eprint/13

Actions (login required)

View Item
View Item