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Electrophysiologic abnormalities in AL (primary) amyloidosis with cardiac involvement.

Reisinger, J, Dubrey, S W, Lavalley, M, Skinner, M and Falk, R H (1997) Electrophysiologic abnormalities in AL (primary) amyloidosis with cardiac involvement. Journal of the American College of Cardiology, 30 (4). pp. 1046-51. ISSN 0735-1097

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Abstract

Patients with cardiac AL are prone to disease in the His-Purkinje system. Prolongation of the HV interval is common and may not be suspected from the surface electrocardiogram in the presence of a narrow QRS complex. These patients have a high prevalence of sudden death, of which the HV interval is an independent predictor. The association of HV prolongation and sudden death is probably multifactorial, representing either a marker of severe myocardial infiltration with an increased propensity to lethal ventricular arrhythmias or electromechanical dissociation, or indicating severe conduction system disease eventually leading to complete atrioventricular block and bradycardic death.
Item Type: Article
Subjects: WG Kardiovaskuläres System
Divisions: Ordensklinikum Linz Barmherzige Schwestern > Interne II - Kardiologie
Depositing User: Dr. Christian Vogel
Date Deposited: 15 Nov 2012 09:08
Last Modified: 15 Nov 2012 09:08
URI: http://eprints.vinzenzgruppe.at/id/eprint/14

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